Family Hotels in Key West & Florida Keys

Updated: December 13, 2025 • By Santorini Dave

The wonderful Tranquility Bay Resort in Marathon is awesome for families.

Best Hotels on Map: 1. Opal Key Resort & Marina • 2. Weatherstation Inn • 3. Gardens Hotel • 4. Lighthouse Hotel • 5. Orchid Key Inn • 6. H2O Suites • 7. Southernmost House • 8. Santa Maria Suites • 9. Casa Marina • 10. Hyatt Residence Club (at Beach House)

Affordable Hotels on Map: 11. NYAH • 12. Southwinds Motel • 13. Fairfield Inn • 14. Hampton Inn

The Best Hotels for Families in Key West & the Florida Keys

1. Santa Maria Suites Resort

Luxurious all-suite hotel in Downtown Key West, within walking distance to South Beach and many Historic Old Town and Duval attractions. Spacious 2-bedroom accommodations with fully-equipped kitchens comfortably sleep families of 5. Resort features onsite Japanese restaurant, bar, 2 heated outdoor pools with complimentary smoothies and fruits, free wine and light snacks at happy hours, and private beach.

2. Hawks Cay Resort

Big family-friendly resort in Duck Key that recently completed major renovations. Amenities include multiple restaurants and bars with live programs, 5 pools, saltwater lagoon, big spa and fitness center, Camp Hawk Environmental Education Program, Dolphin Connection, kiteboarding, and tennis. Family rooms (with bunk beds) are comfortable for families of 4 or 5. Two-bedroom villas are huge and idyllic.

3. Tranquility Bay Resort

Two and three-bedroom houses on the beach in Marathon. Fantastic for large groups and families.

4. Oceans Edge Key West

New family-friendly luxury property 4 miles from downtown Key West. Spacious suites, with 100% ocean views from private balconies, accommodate families of 5 to 10. The resort features 6 pools, open-air waterside restaurant and bar, café serving Starbucks, onsite marina and water activities, complimentary paddleboards and kayaks, and charter of fishing and snorkel boats. Very dog-friendly with 2 dog parks. Provides hourly downtown shuttle.

5. Cheeca Lodge & Spa

Elegant and serene luxury resort spread across 27 acres of lush gardens in Islamorada. Features 525-foot pier for fishing, full-service watersports facility, 9-hole golf course, yoga on the beach, adult and family pools, saltwater lagoon, 3 restaurants, oceanfront Tiki Bar, spa, fitness studio and environmental program for kids. Stylish accommodations with balconies for families of 4 to 6.

6. Reefhouse Resort and Marina

Luxurious and beautiful resort on Key Largo (just one hour from Miami). Spacious rooms and two-bedroom suites can accommodate families of 4 to 7. Onsite amenities include restaurant with kid-friendly menus, pool bar, Tiki Bar, large outdoor pool, fitness center, spa and private beach. It offers a good mix of complimentary and chargeable activities.

More Family Hotels in Key West and Florida Keys

Casa Marina Beach Resort
Historic beach resort in central Key West with large family rooms (one and two bedroom suites). Kid pool, adult-only pool, spa, gym, and water sport facilities.

Hyatt Vacation Club (at Windward Pointe)
Spacious 2-bedroom apartments with full kitchens. Large shallow pool with ocean view.

Coconut Mallory Resort and Marina
Spacious apartments with full kitchens. Two outdoor pools and hot tub. Free parking.